Can I Drink Alcohol While On Pep?

Can I Drink Alcohol While On Pep
This medication can be taken with or without food. This medication can be taken when drinking alcohol or using drugs. Do not share your medication with others. Only studies of daily dosing have shown PEP to be effective.

What should I avoid while taking PEP?

If taken within 72 hours after possible exposure, PEP is highly effective in preventing HIV. But to be safe, you should take other actions to protect your partners while you are taking PEP. This includes always using condoms with sexual partners and not sharing needles, syringes, or other equipment to inject drugs.

Can I drink alcohol while on PrEP?

Can I drink alcohol when taking PrEP? Yes! There is no interaction known between alcohol and PrEP. It is advised to take PrEP during the day, like in the morning after waking up, to ensure the times do not collide with the time that you mostly consume alcohol to reduce the risk of forgetting to take it.

Can I drink alcohol while on Truvada?

There aren’t any known interactions between Truvada and alcohol. However, it’s possible that drinking alcohol may increase your risk of certain side effects of Truvada. * For example, both Truvada and alcohol can cause: nausea.

What stops PEP from working?

Key points –

Randomised studies of PEP have not been done, but experience suggests it is effective in preventing HIV infection. PEP is most effective when it is started soon after exposure to HIV, when doses are not missed and when people complete the 28-day course. The most common cause of HIV infection in people who take PEP is ongoing risk behaviour.

Post-exposure prophylaxis (PEP) is a four-week course of medication that may block HIV infection after exposure to the virus. You can read an overview of PEP here, PEP should not be confused with pre-exposure prophylaxis (PrEP), which involves taking medicine on an ongoing basis, before possible exposure to HIV.

  1. The most accurate way to test the efficacy of PEP would be to conduct randomised trials comparing people taking PEP with people not taking PEP.
  2. However, this has never been considered to be ethically acceptable as it would involve denying people who have been exposed to HIV a treatment that was expected to be effective.

As a result, almost all the evidence on the effectiveness of PEP in humans comes from observational studies, which provide a less robust form of evidence. However, these studies indicate that PEP is highly effective. In 2016, the Centers for Disease Control and Prevention (CDC) in the United States reviewed six observational studies of PEP use by gay, bisexual and other men who have sex with men.

In 40 cases, HIV infection was attributed to ongoing risk behaviour after completing PEP. Among these 40 are 35 cases in which seroconversion occurred more than six months after starting PEP. These HIV transmissions are unlikely to be due to a failure of PEP.8 cases are considered to represent potential PEP failures. This equates to 5.2 transmissions per 1000 PEP users (0.5%).

Even among these eight cases it is not certain that PEP failed. In three cases, very few details of the cases were recorded by researchers. Another four were diagnosed with HIV between three and six months after starting PEP, but no information on their sexual behaviour after finishing PEP was reported – it is possible that they acquired HIV due to further risky sex after completing PEP.

  1. One case might be due to a strain of HIV that was resistant to a drug included in the man’s PEP regimen.
  2. The CDC identified a further 15 studies in other populations, including adults, adolescents and children.
  3. They may have been exposed to HIV through consensual sex, sexual assault, injecting drug use or needlestick injuries, depending on the individual study.

Of the 2209 people who took PEP, 2190 remained HIV negative and 19 were diagnosed with HIV.

In 18 cases, HIV acquisition could be explained by factors such as poor adherence or ongoing risk behaviour. One case was attributed to PEP failure. This relates to a woman who began PEP within four hours of being sexually assaulted and completed the 28-day course, but seroconverted to HIV six weeks after starting PEP.

“Decades of experience has shown PEP to be associated with a substantial reduction in HIV acquisition following condomless sex and needlestick injuries. ” PEP is also used by healthcare workers, after needlestick injuries. The first evidence of PEP efficacy came from a case-control study in 1997 which showed an 81% reduction in the odds of HIV transmission among healthcare workers who received zidovudine as PEP.

  1. Whereas there were 57 confirmed HIV infections among American healthcare workers believed to be due to occupational exposure between 1985 and 1999, there was only one further case between 2000 and 2013.
  2. The reduction in infections was attributed to the greater use of PEP as well as effective treatment of people with HIV and staff training to prevent injuries.

These data are corroborated by animal studies. A meta-analysis, published in 2015, reviewed 16 studies in which one group of primates were exposed to HIV or SIV and then given PEP, with another group exposed but receiving no treatment. The risk of infection was 89% lower among animals given PEP compared with those that did not receive PEP.

Not starting PEP promptly Missing doses of PEP or not finishing the 28-day course A viral strain that is resistant to drugs used in PEP Use of antiretroviral drugs which have sub-optimal penetration of the genital tract (these drugs are no longer recommended) Having unprotected sex, with further exposure to HIV, while taking PEP.

Can alcohol make PEP fail?

Can I drink alcohol while taking PEP? – It is advised that you don’t. Alcohol is processed in the liver and all the PEP drugs can cause liver damage. Best to give it a rest for 28 days. That said, alcohol will not interfere with the activity of the drug and if you have half a glass at a special occasion it is unlikely to do any harm. Avoid binge drinking, your liver will thank you.

Can I drink coffee with PEP?

Answer – Hello and thanks for posting. In short, yes. There are no negative interactions between sodas, tea or coffee with any of the antiretorviral medications (whether used for PEP, PrEP or treatment). I hope that’s helpful, and drink away. BY

Why does PEP fail?

So, if I take PEP I won’t become HIV positive? – Research indicates that taking PEP makes infection with HIV a lot less likely. But PEP doesn’t work every time – some people who take it still end up with HIV afterwards. It can fail because:

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the person doesn’t or isn’t able to take PEP as prescribed (every day for a month) some anti-HIV drugs don’t work against some strains of HIV (although this is rare) the initial viral load (the amount of HIV) in the body was too great for the drugs to be effective

However, the sooner PEP treatment is begun after exposure to the virus, the more likely it is to work. : How Does PEP Work? – Get PEP

What are the side effects of PEP after 28 days?

Key points –

In the UK the recommended first-line PEP medications of emtricitabine/tenofovir and raltegravir are generally well tolerated by most people. Nonetheless, some people do have short-term problems with tiredness, diarrhoea, nausea, flatulence, headache, vivid dreams and other side-effects.

Post-exposure prophylaxis (PEP) is a method of preventing HIV infection. It involves using a four-week course of the drugs used to treat HIV, taken very soon after a person may have been exposed to the virus. PEP consists of three anti-HIV drugs. Two of these medications are from a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs) and are usually taken together in a single pill.

  • A third medication – from either the integrase inhibitor or protease inhibitor class of drugs – is taken separately.
  • It is important to take all three drugs for PEP to be effective.
  • The British Association for Sexual Health and HIV (BASHH) recommends using a fixed-dose combination tablet combining emtricitabine and tenofovir (Truvada, or a generic alternative) from the NRTI class, and raltegravir ( Isentress ) from the integrase inhibitor class.

Previously, BASHH guidelines recommended the protease inhibitor lopinavir/ritonavir ( Kaletra ) in place of raltegravir, but research shows that raltegravir causes fewer side-effects and fewer potential drug-drug interactions, and is associated with better adherence, than lopinavir/ritonavir.

PEP is therefore easier to take than it used to be. This page outlines the possible side-effects of the currently recommended combination of PEP medications, as well as the side-effects of other medications that may be used as alternatives. Side-effects usually appear soon after starting PEP as the body adjusts to the new medications.

Side-effects often lessen, become manageable, or go away completely after a few days or weeks. Another point to bear in mind is that most of these data on side-effects come from HIV-positive people taking the same medications over many years as HIV treatment.

Does PEP work after 72 hours?

What is PEP – Text PEP (sometimes called PEPSE) is a combination of HIV drugs that can stop the virus taking hold. It can be used after the event if you’ve been at risk of HIV transmission. To work, PEP must be taken within 72 hours (three days), and should be taken as soon as possible, ideally within 24 hours.

What happens after finishing PEP?

What happens after I take PEP? – You need to visit your nurse or doctor for follow-up testing after you finish PEP. You’ll get another HIV test 4-6 weeks after you were first exposed to HIV, and then you’ll be tested again 3 months later. Depending on your situation, your doctor may recommend another HIV test 6 months later.

It’s really important to get these follow-up tests to make sure PEP worked. In the meantime, keep protecting yourself and others from HIV by using condoms when you have sex, and not sharing needles or works. We couldn’t access your location, please search for a location. Zip, City, or State Please enter a valid 5-digit zip code or city or state.

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Why can’t you drink alcohol on PrEP?

What Can You Do? – If you drink alcohol:

Drink in moderation. Moderate drinking is up to 1 drink per day for women and up to 2 drinks per day for men. One drink is a 12-ounce bottle of beer, a 5-ounce glass of wine, or a shot of liquor.Visit Rethinking Drinking, a website from NIH’s National Institute on Alcohol Abuse and Alcoholism (NIAAA). This website can help you evaluate your drinking habits and consider how alcohol may be affecting your health.Don’t have sex if you’re drunk or high from other drugs.If you are HIV-negative, talk to your health care provider about pre-exposure prophylaxis (PrEP), PrEP is medicine people at risk for HIV take to prevent getting HIV from sex or injection drug use. PrEP can stop HIV from taking hold and spreading throughout your body. PrEP must be taken as prescribed and alcohol use can make it hard to stick to an HIV regimen. Be open and honest about your alcohol use so you and your doctor can develop a plan for you to stick to your HIV medicine.If you aren’t taking PrEP as prescribed, condom use is also important to help prevent HIV. And, since PrEP only protects against HIV, condom use is still important for the protection against other sexually transmitted infections (STIs). Read this fact sheet from the Centers for Disease Control and Prevention (CDC) on how to use condoms correctly. You can also consider sexual activities that are lower risk for HIV than anal or vaginal sex (like oral sex).If you have HIV, take HIV medicine (called antiretroviral therapy or ART) as prescribed. People with HIV who take HIV medication as prescribed and get and keep an undetectable viral load can live long and healthy lives and will not transmit HIV to their HIV-negative partners through sex,

Need help?

If you feel you are drinking too much, too fast, or too often, therapy and other methods are available to help you stop or cut down on your alcohol use (if you have a problem). Talk with a counselor, doctor, or other health care provider about options that might be right for you.The National Institute on Alcohol Use and Alcoholism (NIAAA) offers an Alcohol Treatment Navigator, This online tool helps you find the right treatment for you—and near you. It guides you through a step-by-step process to finding a highly qualified professional treatment provider.You can also use the SAMHSA Behavioral Health Treatment Locator or call 1-800-662-HELP (4357). Open 24/7.

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Is Truvada hard on your liver?

Truvada is an antiretroviral medication that doctors prescribe for the prevention and treatment of HIV infections. However, the drug can have some serious side effects for patients, including liver damage. According to the Food and Drug Administration (FDA), there is proof of a link between liver damage and Truvada use.

While some of those taking the medication may only experience mild liver damage, others could have severe problems, including liver failure. The FDA also mentions a potential link between Truvada and liver cancer. It is now clear that Truvada can cause liver damage. If you experienced serious liver issues after taking Truvada and had financial losses as a result, you can consult a Truvada lawsuit lawyer.

You could potentially recover compensation.

How often does PEP fail?

Results – 3547 PEP consults were included. Patients were mainly male (92%), MSM (83%) and sought PEP for anal intercourse (72%). Seventy-eight percent (n = 2772) of patients received a prescription for PEP, consisting of Tenofovir/Emtracitabine (TVD) + Lopinavir/Ritonavir (LPV) in 74% of cases, followed by Zidovudine/Lamivudine (CBV) + LPV (10%) and TVD + Raltegravir (RAL) (8%).

Seventy percent of patients were adherent to treatment. Compared to TVD+LPV, patients taking CBV+LPV were less likely to adhere to treatment (OR 0.58, 95% CI 0.44–0.75), while no difference was observed for patients taking TVD+RAL (OR 1.15, 95% CI 0.83–1.59). First-time PEP consults, older and male patients were also more adherent to treatment.

Ten treated patients seroconverted (0.37%) during the study period, yet only 1 case can be attributed to PEP failure (failure rate = 0.04%).

Why is PEP 28 days?

Someone asked the other day about why is it necessary to take post-exposure prophylaxis for 28 days. The person had heard that PEP meds were hard on the liver and immune system, and so 28 days seems like a long time. This is a good Sexual Health question.

  • Most of the science behind the 28-day recommendation comes from animal studies and small studies of health care workers who did not complete the 28-day course of treatment.
  • HIV attaches to human cells depending on the amount of virus entering the body after a sexual encounter.
  • HIV also attacks different parts of the body on different schedules – sometimes taking as long as a week to attach completely.

The goal of PEP is to kill virus and stop its attachment to cells. This works best if PEP is given as soon as possible after condomless anal sex; with best results when PEP is started within 72 hours of exposure. The 28-day schedule is used to give PEP the best chance of working, and 28 days is considered short-term.

After more than 20 years of giving PEP, I’ve found that most side effects are stomach upset that lasts a few days, then goes away. Liver problems can happen occasionally, and we look for this with blood testing before starting and at the end. If needed, we can check blood during the 28 days of treatment.

The other good news is that the drugs used for PEP, PrEP and HIV treatment attack HIV without doing harm to the immune system. In fact, when used for treatment, HIV drugs improve the immune system by clearing virus and restoring T-cell numbers. The article that I suggest is a long discussion, but answers all the questions – Check out a shorter version from CDC –

Is PEP time sensitive?


  • EXPOSURE TO HIV IS A MEDICAL EMERGENCY: PEP should be initiated immediately—ideally within 2 hours of an exposure but no later than 72 hours after an exposure—because the effectiveness of PEP decreases over time after 2 hours.
  • Assessment of exposure, HIV and other baseline testing, and other related activities can proceed after the first dose of PEP is administered.

In addition to clinical recommendations, this guideline details selected good practices and highlights laws and legal considerations that are pertinent in delivering PEP care. Goals: This guideline aims to achieve the following goals:

  • Prevent HIV infection in individuals who experience a high-risk exposure.
  • Reinforce that HIV exposure is an emergency that requires rapid response, with immediate administration of the first dose of PEP medications.
  • Reduce under- and over-prescribing of PEP by describing the benefits of PEP and providing guidance for identifying high-risk HIV exposures for which PEP is indicated.
  • Ensure prescription of PEP regimens that are effective and well tolerated.
  • Assist clinicians in recognizing and addressing challenges to successful completion of a PEP regimen.
  • Detail the baseline testing, monitoring, and follow-up that should accompany prescription of a 28-day course of PEP.
  • Assist clinicians in managing potential concurrent exposures to hepatitis B virus (HBV) and hepatitis C virus (HCV).

How to use this guideline: This guideline is organized to support rapid location of key topics, such as when to initiate PEP, how to evaluate whether continuation of PEP is necessary based on specific risk factors, source testing, how to choose and prescribe a PEP regimen, and recommendations for follow-up care for exposed individuals.

  1. The NYSDOH AI Medical Care Criteria Committee recommendations for prescribing PEP are based on a comprehensive review of available published evidence.
  2. In formulating recommendations for NYS, this Committee balanced the strength of published evidence regarding efficacy and timing of initiation of the PEP regimen.

See the Guideline Development and Recommendation Ratings for a description of the development and ratings processes.

Can PEP damage kidneys?

Answer – Answer: Josh Peasegood Hi, how are you doing? Had you had a kidney function test prior to taking PEP? Tenofovir is known to cause kidney damage however this is commonly in those with an already damaged kidney. It would also not be expected to occur this fast.

How hard is PEP on your body?

Take care of yourself

PEP drugs are very hard on the immune system. You will need to take special care to stay healthy: plenty of sleep and lots of nutritious food will help your body fight off infection. Everyone experiences PEP side effects differently. Depending on the severity of the side effects for you, you might want to take some time off work or school.

Follow your doctor’s instructions exactly

PEP is only effective if you take the medicine as instructed. PEP will work best when taken at the right dose, at the right time, without fail. If you still have questions after you’ve been prescribed PEP, talk to your doctor or healthcare provider right away. Do not stop taking your prescribed doses.

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Make a plan for taking your PEP medicine on time

It is critical you take your PEP medication at the correct time, and at the correct dose. Consider using your phone’s alarm clock, a watch alarm or a computer reminder to make sure you don’t forget. Keep your PEP medication in the open so you don’t forget about it.

Try not to miss a dose

If you miss a dose, take it as soon as you remember – do not wait for the next scheduled dose and “double up”. PEP drugs are very hard on your body; never take more than one dose at one time. It is very important to take your doses on time. When PEP fails to destroy HIV, it is often because of missed doses.

Prepare for side effects

PEP has side effects, which can vary from person to person. The most common side effects include nausea, vomiting, diarrhea, headaches and fatigue. If the PEP side effects become too much to handle, talk to your doctor or healthcare provider. Do not stop taking PEP, and do not miss a dose without speaking to your doctor or healthcare provider.

Other drugs and PEP

Make sure your doctor or healthcare provider knows about all prescription drugs you’re taking before you begin taking PEP. It is important to eliminate or reduce recreational drug use while you’re on PEP; these drugs can damage your immune system, and your body can react differently to many of these drugs while on PEP.

Storing your PEP medicine

Ask your doctor about proper storage for your PEP medicine (generally speaking, you can keep them anywhere that is cool, dark and dry). Don’t keep PEP medicine in the bathroom, as it might be too moist.

Does PEP damage the body?

What tests Are needed? – Blood tests will be taken to check if you already have HIV and also to check your liver and kidneys because PEP can rarely cause liver or kidney damage. You may also be offered tests for other STI’s such as chlamydia, gonorrhoea and syphilis.

Can I smoke after taking PEP?

There is no interaction between your combination of PEP and marijuana.

Can I do gym while taking PEP?

Hi, You can do gym and other day to day activities. No issues as such.

Can I test positive while on PEP?

Answer – Answer: Josh Peasegood Hi M, How are you doing? Starting PEP as early as you did means you are within the time frame for it to be most effective. Also, being the ‘top’ further reduces your risk, as does not ejaculating and there being no presence of blood.

  1. Using lubrication further reduces risk as it reduces the risk of abrasion from friction.
  2. These factors means it is very unlikely you will test positive for HIV.
  3. As you have mentioned, a test while on PEP is not accurate.
  4. This is because PEP can ‘mask’ HIV and will not give a true representation of your status.

To be sure you will need to wait 6 weeks until after your course to know your status. In the meantime, this guide discusses feelings of fear and anxiety while awaiting results. The symptoms you have mentioned are possible signs of seroconversion. Also they are signs of many other infections.

  • Due to how non-specific symptoms are for HIV, it is impossible to say if you are seroconverting.
  • If these symptoms are in association with the time you take PEP, it is more likely a side effect of the medication.
  • I am sorry to hear that you are in this alone.
  • Do you have any family/friends that you are able to discuss this with? The Terrance Higgin’s Trust in the UK offer an email service that may be suitable in this instance.

It is unfortunate to hear about the lack of support you are having from your doctors, but if you become increasingly concerned with your health you need to make sure you speak to them. This is the only way you can be sure of your current state of health.

Can PEP be taken with other drugs?

Does PEP Cause Side Effects? – PEP is safe, but the HIV medicines used for PEP may cause side effects like nausea in some people. In almost all cases, these side effects can be treated and aren’t life-threatening. If you are taking PEP, talk to your health care provider if you have any side effect that bothers you or that does not go away.

Can I take PEP on an empty stomach?

To prevent nausea, take PEP with a snack or before bed to make nausea less noticeable.

Can I take paracetamol while on PEP?

antiretroviral (ARV) – A substance that acts against retroviruses such as HIV. There are several classes of antiretrovirals, which are defined by what step of viral replication they target: nucleoside reverse transcriptase inhibitors; non-nucleoside reverse transcriptase inhibitors; protease inhibitors; entry inhibitors; integrase (strand transfer) inhibitors.

Anti-HIV medications can also interact with herbal and alternative treatments. For example, St John’s wort, a herbal remedy used to treat anxiety and depression, lowers blood levels of NNRTIs and PIs. It can cause them not to work effectively and there’s a risk of developing resistance, In many cases, the interactions are theoretical, or seen in test-tube studies, and more information is needed about the likelihood of a real-life effect.

For example, test-tube studies have indicated that African potato and Sutherlandia may reduce levels of PIs, NNRTIs and maraviroc ( Celsentri ) in the body. Interactions can also happen with medicines that are not taken by mouth. For example, ritonavir and cobicistat can interact with inhalers and nasal sprays containing fluticasone, budesonide, mometasone, or salmeterol (e.g.

Flixotide, Flixonase, Pulmicort, Seretide, Serevent, Nasonex, Pirinase ), used to treat asthma and hay fever, potentially causing serious side-effects. Cetirizine ( Piriteze, Benadryl One-A-Day, Zirtek and Pollenshield ) is a safe antihistamine to take with anti-HIV medications and can be bought over the counter or prescribed by your GP.

You can safely take some painkillers, such as paracetamol, when on anti-HIV medications, unless there are other medical reasons why you shouldn’t take this sort of drug. Check with your HIV doctor or pharmacist about the best type of painkiller for you.

Does PEP affect sleep?

PEP medications, in particular raltegravir, are known to have a common side effect of insomnia.